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Purpose: To analyse the predisposing factors, microbial profiles, source of infection, and visual outcomes of endogenous endophthalmitis seen in Hospital Sultanah Aminah Johor Bahru (Johor, Malaysia).

Study design: Retrospective review.

Methods: The medical records of 15 patients, of which 19 eyes were diagnosed with endogenous endophthalmitis, admitted from January 2014 to December 2018 were retrospectively reviewed.

Results: The mean age was 55.9 ± 12.7 years (range: 31-78 years of age). There were four patients (26.7%) with bilateral involvement. Diabetes mellitus was the commonest risk factor in this study (odds ratio: 16; 95% confidence interval: 1.09-234.26). The most common source of infection was urosepsis (n = 3, 20%) followed by liver abscesses (n = 2, 13.3%), Klebsiella pneumoniae being the most common microorganism isolated (n = 4, 44.4%). Only 10.5% of eyes (n = 2) had a final Snellen visual acuity better than 6/60, while 47.4% of eyes (n = 9) had vision of no light perception.

Conclusion: In this study, Klebsiella pneumoniae was the most common organism. Overall, endogenous endophthalmitis is associated with poor visual outcomes.

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