- Abstract viewed - 0 times
- PDF downloaded - 0 times
Abstract
Purpose: We conducted a retrospective study of keratoconus patients who underwent either penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK) in Malaysia from 2014 to 2018 to compare refractive and visual outcomes between PKP and DALK.
Study design: Retrospective case control study.
Methods: We studied 59 eyes of 53 keratoconus patients: 31 eyes underwent PKP and 28 underwent DALK. We obtained data that included demographic distribution, pre- and postoperative best-corrected visual acuity (BCVA in logMAR), postoperative refraction (spherical equivalent and astigmatism), postoperative topography (SimK1, SimK2, and Kcyl), type of correction (spectacles versus contact lens), incidence of rejection, and other complications.
Results: There were 22 female patients (42.0%) and 31 male patients (58.0%) with 55.0% Indians, 34.0% Malays, 7.0% Chinese, and 4.0% others. The mean age was 27.03 ± 8.68 years for the PKP group and 26.36 ± 7.26 years old for the DALK group (p = 0.784). There were no statistically significant differences in preoperative BCVA, postoperative refraction, and postoperative topography. However, there was a statistically significant difference in postoperative BCVA between PKP (0.16 ± 0.16) and DALK (0.33 ± 0.17) (p = 0.001). Graft rejection was a significant complication in the PKP group, with 5 eyes (16.0%) resulting in 2 graft failures (6.0%).
Conclusions: In this study, more men than women underwent corneal transplant for keratoconus within the second to third decades of life, most of whom were of Indian origin. PKP showed better visual outcome in terms of BCVA than DALK. Regarding refractive and keratometry parameters, there were no significant differences. However, DALK had a lower rate of graft rejection and graft failure compared to PKP.