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Submitted: 2022-11-11
DOI: 10.35119/myjo.v6i2.334
Case Reports
Published: 2024-06-27

Symptomatic pigment dispersion with intraocular pressure elevation attributed to intracameral moxifloxacin after open-globe injury

Loma Linda University School of Medicine, Loma Linda, CA, USA
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
bilateral acute iris depigmentation intracameral moxifloxacin pigment dispersion

Abstract

Background: Intracameral moxifloxacin is commonly used following intraocular surgery to prevent endophthalmitis. Pigment dispersion is a rare complication of moxifloxacin use that has mainly been reported following systemic administration.

Case presentation: We report a case of unilateral pigment dispersion three weeks after open-globe repair with intracameral moxifloxacin presenting with pain, redness, photophobia, elevated intraocular pressure, marked pigment liberation, new iris transillumination defects and pigment deposits on the anterior iris surface.

Conclusion: Symptomatic unilateral pigment dispersion with IOP elevation following intracameral moxifloxacin is a rare entity, but it is a crucial complication for clinicians to be aware of as intracameral antibiotic use following intraocular surgery becomes more frequent.